Work

Potential of oral combination lipid‑lowering therapy beyond statins: a simulation‑based perspective from the SANTORINI study

Year: 2026

Type: article

Abstract: Sequential theoretical addition of ezetimibe and bempedoic acid increased LDL‑C goal achievement and was associated with modeled reductions in MACE. Risk estimates were inferred from LDL‑C lowering in the simulation.Image, graphical abstract.

Source: American Journal of Preventive Cardiology

DOI: 10.1016/j.ajpc.2026.101596

Author: Raul D. Santos

Institutions: Universidade de São Paulo, Hospital Israelita Albert Einstein, Hospital Universitário da Universidade de São Paulo, Instituto do Coração - HCFMUSP

Language: English

Topic: Lipoproteins and Cardiovascular Health

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,900