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Statins as an Adjuvant Therapy for Psychotic Disorders: Current Evidence with a Systematic Overview of Double-Blind Placebo Controlled Trials

Year: 2017

Type: article

Abstract: Evidence is accumulating that inflammatory processes play a role in the pathophysiology of schizophrenia. This suggests that anti-inflammatory drugs might have beneficial effects in the treatment of schizophrenia patients. Statins have cholesterol independent effects on inflammation and oxidative stress and could potentially improve positive, negative and/or cognitive symptoms of schizophrenia. We provide an overview of the literature regarding the effects of statins in the treatment of schizophrenia.

Source: Journal of Brain Disorders

DOI: 10.36959/524/325

Authors: Postma Tjardo S, Nasib Lyliana G, Schutte Maya J L, Bohlken Marc M, Martens Peter, Hag Erna van't, Veerman Selene R T, Begemann Marieke J H, Sommer Iris E C

Language: English

Topic: Schizophrenia research and treatment

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W2998443029

FWCI:

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