Work

Tongue Sarcoidosis: A Rare Case Report and Review of the Literature

Year: 2026

Type: article

Abstract: This study presents a case report with a literature review describing a rare manifestation of oral sarcoidosis involving the tongue in a 57-year-old woman with a prior diagnosis of cutaneous sarcoidosis. The lesion appeared as painless grayish-white papules on the tip and dorsal surface of the tongue. A review of the reported cases of tongue sarcoidosis indicates lesions usually occur during the fifth and sixth decades of life, with a marked predominance in females. The most observed signs were swelling and nodules, which commonly affect the tip and dorsal surfaces, in contrast to the usual sites of oral squamous cell carcinoma. Various approaches have been described for managing oral sarcoidosis, ranging from observation without treatment to pharmacological (steroids/immunosuppressive) and surgical interventions. Since in many cases, oral lesions constitute the initial manifestation of sarcoidosis, as well as the wide variety of clinical symptoms and involvement of vital organs/systems (e.g., pulmonary, cardiac, lymph nodes) in the majority of sarcoidosis patients, dentists should regularly examine oral cavity, pay attention to the signs and symptoms of the disease, obtain biopsies of lesions if suspicious, and refer the patient to the relevant specialist.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.72439

Authors: Saede Atarbashi‐Moghadam, Leyla Roghanizadeh, Ali Lotfi, Mehrab Aghdasi, Mohammadreza Kashefi Baher

Institutions: Shahid Beheshti University, Shahid Beheshti University of Medical Sciences, Chamran Hospital

Language: English

Topic: Sarcoidosis and Beryllium Toxicity Research

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820