Work

Computational discovery and preclinical validation of a novel nanodrug eEF2 kinase inhibitor for suppression of tumor growth in triple-negative breast cancer by induction of ferroptosis and apoptosis

Year: 2026

Type: article

Source: International Journal of Biological Macromolecules

DOI: 10.1016/j.ijbiomac.2026.151860

Authors: Ferah Comert Onder, Nermin Kahraman, Pinar Siyah, Serdar Durdağı, Esen Bellur Atici, Pinar Atalay, Sayra Dilmac, Rumeysa Ozyurt, Goknur Kara, Ogun Gul, Izabela Fokt, Waldemar Priebe, Mustafa Guzel, Mehmet Ay, Bulent Ozpolat

Institutions: Çanakkale Onsekiz Mart Üniversitesi, The University of Texas MD Anderson Cancer Center, Bahçeşehir University, Biruni University, Houston Methodist, Houston Methodist Research Institute, Istanbul Medipol University, University of Oklahoma

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, National Institutes of Health, National Cancer Institute

Awards: G2577015486, G3274534390

OpenAlex ID: W7150776190

FWCI: 3.591

Cites: 52

Cited by: 1

Related to: 10