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Zone-specific hepatocytes orchestrate the early onset of host defence mechanisms during Staphylococcus aureus bloodstream infection

Year: 2025

Type: dataset

Abstract: In this study, we investigated the transcriptional response of the liver to blood-borne Staphylococcus aureus infection in mice. Mice were infected intravenously with the S. aureus strain SH1000, and the hepatic transcriptional response was analyzed at 4 and 24 hours after bacterial inoculation using RNA-seq

Source: Harvard Dataverse

DOI: 10.7910/dvn/34g5ow

Authors: Medina, Eva, Nwofor, Obiageli Vivian, Leipold,, Chen, Qian, Geffers, Robert, Saliba, Antoine-Emmanuel, Goldmann, Oliver

Institutions: Helmholtz Centre for Infection Research, Helmholtz Institute for RNA-based Infection Research

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7150855217

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