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LMTK3 as a spatially regulated and stage-dependent biomarker in epithelial ovarian tumorigenesis

Year: 2026

Type: article

Abstract: = 0.047). LMTK3 expression and subcellular localization evolve during ovarian tumorigenesis. These patterns carry stage-specific prognostic implications, supporting LMTK3 as a spatially resolved biomarker for EOC stratification.

Source: Molecular Therapy Oncology

DOI: 10.1016/j.omton.2026.201199

Authors: Ella Ittner, Lucas Werner, Hugo Swenson, Anna Linder, Karin Sundfeldt, Ghassan Saed, Per Karlsson, Toshima Z. Parris, Anikó Kovács, Khalil Helou

Institutions: University of Gothenburg, University of Jordan, Wayne State University, The Barbara Ann Karmanos Cancer Institute, Sahlgrenska University Hospital, Region Västra Götaland

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funders: Cancerfonden, Stiftelsen Konung Gustaf V:s Jubileumsfond, Stiftelsen Jubileumsklinikens Forskningsfond mot Cancer

Awards: G4115856172, G7403567097, G8100273983

OpenAlex ID: W7150912345

FWCI:

Cites: 28

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