Work

Diagnostic Pitfalls and Lessons Learned in Portal Hypertension

Year: 2026

Type: article

Abstract: Noncirrhotic portal hypertension is defined as portal hypertension in the absence of cirrhosis or advanced hepatic fibrosis. We present an 85-year-old man with recurrent hematemesis, initially presumed to have decompensated cirrhosis based on imaging. However, liver biopsy revealed pseudocirrhosis due to sinusoidal infiltration by metastatic spindle cell malignancy. This case underscores the importance of histological confirmation when imaging suggests cirrhosis, as infiltrative malignancies can mimic cirrhosis and produce clinically significant portal hypertension.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000002076

Authors: Alekhya Mannava, Wendy Liu, Shahrazad Saab, Resham Ramkissoon

Institutions: University Hospitals Cleveland Medical Center, Case Western Reserve University

Language: English

Topic: Liver Disease and Transplantation

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7151094422

FWCI:

Cites: 8

Cited by:

Related to: