Work

Amelioration of Diabetic Dyslipidaemia by an Aqueous Extract of Tremella fuciformis in Streptozotocin-Induced Diabetic Mice

Year: 2026

Type: article

Abstract: Diabetic dyslipidaemia is a major contributor to cardiovascular risk in insulin-deficient states. This study evaluated the hypolipidemic activity of an aqueous extract of Tremella fuciformis (AETF) in streptozotocin (STZ)-induced diabetic mice. Male BALBc mice were rendered diabetic by a single intraperitoneal injection of STZ at a dose of 60 mgkg body weight. Hyperglycaemic animals exhibiting fasting blood glucose levels 250 mgdL were selected and administered AETF orally at doses of 50 and 100 mgkg body weight per day for 28 consecutive days. Serum lipid parameters were quantified using enzymatic colourimetric assays. The STZ administration induced significant dyslipidaemia, characterised by elevated triglycerides, total cholesterol, LDL-C, and VLDL-C, along with reduced HDL-C, compared with normal controls (p

Source: Journal of Veterinary and Animal Sciences

DOI: 10.51966/jvas.2026.57.1.208-216

Authors: Zahid Ahmad Wani, Asvene Kumar Sharma, Showkeen Muzamil, Yaqoob lone

Institutions: Shri Venkateshwara University, Sri Venkateswara University

Language: English

Topic: Fungal Biology and Applications

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7152128545