Aortic Sinus Dissection Causing STEMI
Year: 2026
Type: article
Study design: Case Report
Abstract: BACKGROUND: Localized aortic sinus dissection is a rare cause of acute coronary syndrome that is often undetected on initial imaging. CASE SUMMARY: A 72-year-old man with aortic root aneurysm presented with acute inferior ST-segment elevation myocardial infarction (STEMI). Initial computed tomography was negative for aortic dissection, however angiography revealed total occlusion of the right coronary artery (RCA) owing to coronary artery dissection. Percutaneous coronary intervention (PCI), challenging given an anomalous RCA ostium, successfully stented the occlusion. Subsequent high-resolution coronary computed tomography angiography identified right aortic sinus intimal tears extending into the RCA ostium; retrospective review of pre-PCI imaging confirmed dissection. The patient underwent Bentall surgery with RCA bypass. DISCUSSION: This case highlights a localized aortic sinus dissection mimicking primary coronary disease, emphasizing the importance of advanced imaging and the role of adaptive PCI as a bridge to definitive surgery. TAKE-HOME MESSAGES: Localized aortic sinus dissection can mimic acute STEMI and should be considered in patients with known aortic root disease, even when initial imaging appears unremarkable. High-resolution coronary computed tomography angiography is diagnostic; PCI for anomalous ostia may require advanced techniques. A heart team approach is vital for staged management.
Source: JACC Case Reports
Authors: Jiabao Liu, Haoyu Meng, Hao Wang, Xiaomei Zhu, Liansheng Wang, Qiming Wang
Institutions: Jiangsu Province Hospital, Nanjing Medical University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $850
OpenAlex ID: W7152534673
