Work

Interspecies competition promotes antibiotic resistance with diminishing returns

Year: 2026

Type: article

Abstract: Evolutionary outcomes are affected by multiple complex factors, many of which are omitted from traditional experimental designs. In their recent manuscript, Muzafar et al. demonstrate that interspecies competition drives increased physiological streptomycin resistance in Salmonella enterica through upregulation of the stringent stress response, altering evolutionary trajectories between monoculture and coculture.

Source: Trends in Microbiology

DOI: 10.1016/j.tim.2026.03.014

Authors: Emma K. Sheriff, Ville-Petri Friman

Institution: University of Helsinki

Language: English

Topic: Bacterial Genetics and Biotechnology

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $7,030

Funder: Novo Nordisk Fonden