Work

Clinical approaches to hypersomnolence complaints in psychiatry: A narrative review

Year: 2026

Type: review

Abstract: BACKGROUND: Hypersomnolence complaints are common in psychiatric disorders and carry substantial functional burden, yet they remain under-recognized and frequently under-investigated. Clinically, hypersomnolence spans three partially overlapping dimensions: excessive daytime sleepiness, excessive total sleep time/need for sleep, and sleep (wake) inertia. OBJECTIVE: To provide a pragmatic, clinician-oriented framework for evaluating and managing hypersomnolence complaints in psychiatry, integrating sleep medicine concepts with psychiatric comorbidity and real-world care pathways. METHODS: Narrative synthesis of epidemiological, clinical, and translational evidence with emphasis on: (i) precise phenotypic clarification of the complaint; (ii) systematic etiological work-up (sleep debt and circadian misalignment, depressive episodes, ADHD, anxiety/trauma-related disorders, iatrogenic factors, OSA, RLS, parasomnias, narcolepsy/idiopathic hypersomnia); and (iii) stepwise management strategies. RESULTS: Hypersomnolence affects 40-50% of patients in major depressive episodes and is frequently linked to circadian factors, insomnia comorbidity, obstructive sleep apnea, and medication effects. Objective long sleep time is common among depressed patients with hypersomnolence. Similar observations are made for ADHD, anxiety and trauma-related disorders and psychotics disorders. A three-step care algorithm is proposed: (1) universal behavioral/circadian measures; (2) targeted treatment of the underlying cause (e.g., antidepressant optimization, chronotherapeutics, CBT-I, CPAP/MAD for OSA, specific management for RLS/parasomnias, and specialist evaluation for narcolepsy/idiopathic hypersomnia); (3) management of residual symptoms (e.g., light therapy; carefully selected wake-promoting agents when indicated). CONCLUSIONS: A fine-grained clinical characterization coupled with systematic etiological screening improves diagnosis and treatment of hypersomnolence in psychiatry. Integrating sleep-specific tools (actigraphy, sleep diaries, MSLT/PSG when appropriate) with psychiatric assessment supports personalized, mechanism-informed care and may reduce morbidity, accident risk, and healthcare utilization.

Source: L Encéphale

DOI: 10.1016/j.encep.2026.03.002

Authors: Pierre A. Geoffroy, Nausicaa Christodoulou, Jean-Arthur Micoulaud Franchi, Julia Maruani