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Beyond the Colon: Clostridioides d ifficile Enteritis Presenting Following a Nissen Fundoplication

Year: 2026

Type: article

Abstract: Clostridioides difficile enteritis (CDE) is a rare condition usually seen in patients with recent abdominal surgery and/or antibiotics. A 49-year-old male patient presented following a Nissen fundoplication surgery with watery diarrhea, abdominal pain, tenderness, tachycardia, and hypotension. Stool polymerase chain reaction for C. difficile was positive, enzyme immunoassay negative. Abdominal CT was suggestive of enteritis. He was treated with a course of oral vancomycin. This study highlights that CDE can occur following other surgeries apart from ileostomy/colectomy and should be on the differential for high-risk patients (hospitalization, proton pump inhibitor (PPI) use, and antibiotic exposure).

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000002081

Authors: Fnu Alvina, Dayana Nasr, Kelita Singh

Institution: SUNY Upstate Medical University

Language: English

Topic: Clostridium difficile and Clostridium perfringens research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7152895126

FWCI:

Cites: 7

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