Pediatric Submandibular Lymphadenitis Caused by Mycobacterium houstonense: A Case Report and Literature Review
Year: 2026
Type: article
Study design: Case Report
Abstract: Minxue Liu,1,* Jing Guo,1,* Yan Chen,1 Xuehua Hu,1 Xiaocheng Luo,2 Lian Ma,2 Liying Huang1 1Department of Laboratory Medicine, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning, People’s Republic of China; 2Department of Laboratory Medicine, Nanning Fourth People’s Hospital, Guangxi AIDS Clinical Treatment Center (Nanning), Nanning, People’s Republic of China*These authors contributed equally to this workCorrespondence: Liying Huang, Department of Laboratory Medicine, Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region, Nanning, People’s Republic of China, Email [email protected]: Infection caused by Mycobacterium houstonense is rare. A literature review suggested that M. houstonense infections mainly affect adults with open fractures or wounds. Here, we report a pediatric case of submandibular lymphadenitis caused by M. houstonense. The strain was identified using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) and 16S rRNA gene sequencing. The patient was successfully treated with a six-month combination regimen of linezolid, clarithromycin, amikacin, and cefoxitin, with the modification that trimethoprim-sulfamethoxazole was used instead of cefoxitin for the final four months. The pediatric patient was monitored monthly with complete blood counts and liver function tests throughout the treatment course. No adverse events were observed, and clinical cure was achieved.Keywords: Mycobacteria houstonense, pediatric patient, infection, lymphadenitis, case report
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7153408055
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