Year: 2026
Type: article
Abstract: Recent advances in the development of in-body bioelectronic systems are providing new opportunities for the clinical management of various diseases and disorders. These emerging technologies are tailored to specific organs and are beginning to blend both diagnostic sensing and therapeutic actuation. The aim of these systems is to seamlessly integrate with the physiological environment, as illustrated by the diverse device strategies discussed throughout this article. Next generation modalities, such as optogenetics combining gene therapy with devices for photostimulation, are gaining popularity and offer advantages over existing therapeutic strategies. In this perspective, we explore the current state of technological developments, key challenges in the field and potential pathways for translating these innovations into clinical practice.
Source: Nature Communications
Institutions: Wyss Center for Bio and Neuroengineering, University of Lausanne, Northwestern University, New York University Abu Dhabi, New York University, Leibniz Institute of Polymer Research, Center for Regenerative Therapies Dresden, Technische Universität Dresden, Else Kröner Fresenius Center for Digital Health, Brigham and Women's Hospital, Harvard University, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology, Centre National de la Recherche Scientifique, Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie, Université de Strasbourg
Language: English
Subfield: Cellular and Molecular Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $6,990
Funders: National Science Foundation, Novartis Foundation, European Commission, International Foundation for Research in Paraplegia, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Innosuisse - Schweizerische Agentur für Innovationsförderung, Horizon 2020 Framework Programme
OpenAlex ID: W7153433418