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Laparoscopic Cholecystectomy for Acute Cholecystitis: An Evidence-Based Review

Year: 2026

Type: article

Abstract: Laparoscopic cholecystectomy (LC) is currently considered the standard treatment for acute cholecystitis, although controversies persist regarding optimal timing, management of severe disease, and treatment in high-risk populations. This review summarizes current evidence on the effectiveness, safety, and indications of LC compared with open surgery and percutaneous drainage. Available data consistently demonstrate that LC is associated with lower morbidity, mortality, and shorter hospital stay compared with open cholecystectomy. Early LC is generally favored, as it reduces complications and overall hospitalization. However, in severe inflammation or high-risk patients, complication rates and conversion to open surgery increase, and alternative strategies such as percutaneous cholecystostomy may be appropriate. Outcomes are strongly influenced by surgical expertise and patient selection. Overall, LC remains the preferred treatment for most patients with acute cholecystitis, provided that appropriate clinical judgment and bailout strategies are applied in complex cases.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.19509989

Authors: Juan Pablo Rubén Quiroga Cruz, Mario Lujano González, José Luis Castro Trejo, Karla Daniela Martínez García, Emily Villagomez Guzmán

Institution: Universidad Autónoma de Guadalajara

Language: English

Topic: Gallbladder and Bile Duct Disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7153657788

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