Work

Three-Color SUVLV-Normalized SPECT/CT to Visualize Dynamic Pulmonary Perfusion in Chronic Thromboembolic Pulmonary Hypertension

Year: 2026

Type: article

Abstract: Background: Conventional lung perfusion scintigraphy relies on relative tracer distribution and has limited utility for longitudinal assessment of regional pulmonary perfusion in chronic thromboembolic pulmonary hypertension (CTEPH). Methods and Results: )-based 3-color SPECT/CT mapping in a patient with CTEPH undergoing staged balloon pulmonary angioplasty followed by pulmonary endarterectomy. This approach visualized regional perfusion redistribution and vascular steal patterns not clearly identified by conventional SPECT/CT and demonstrated close spatial concordance with pulmonary angiographic findings throughout multimodal treatment. Conclusions: -normalized 3-color SPECT/CT enables intuitive visualization of dynamic pulmonary perfusion redistribution during staged interventions.

Source: Circulation Reports

DOI: 10.1253/circrep.cr-26-0041

Authors: Daiki Kishigami, Hiroto Shimokawahara, Kazunori Takahashi, Soichiro Kobashi, Hiromi Matsubara

Institution: Okayama Medical Center

Language: English

Topic: Pulmonary Hypertension Research and Treatments

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond