Work

Neurotrophic ulcer as the presenting symptom of central nervous system invasion in precursor B-cell lymphoblastic leukemia: a case report

Year: 2026

Type: article

Abstract: It is not uncommon that ophthalmologists encounter life-threatening conditions masquerading as common ocular complaints. We present a case of a 33-year-old male with neurotrophic corneal ulcer as the initial symptom of intracranial spread of precursor B-cell lymphoblastic leukemia. This was rapidly followed by affection of nerves VI, III on the right side, and II, VII on the left side. Work-up included MRI, magnetic resonance venography, and cerebrospinal fluid analysis to exclude various causes of multiple cranial neuropathies. Cerebrospinal fluid analysis revealed the presence of malignant cells, and intrathecal chemotherapy was initiated.

Source: Journal of the Egyptian Ophthalmological Society

DOI: 10.4103/ejos.ejos_67_25

Author: Rawan Hosny

Institutions: Cairo University, Cairo University hospitals

Language: English

Topic: CNS Lymphoma Diagnosis and Treatment

Subfield: Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7154111349

FWCI:

Cites: 9

Cited by:

Related to: