Advances in Carbon Dot-Based Optical (Bio)Sensors for Contaminant Detection in Wastewater-Based Epidemiology
Year: 2026
Type: article
Abstract: Wastewater-based epidemiology (WBE) has emerged as a powerful approach for population-level monitoring of chemical exposure, health status, and disease transmission by analysing wastewater. Although chromatographic and molecular techniques remain the gold standard in WBE, their high cost, infrastructural demands, and limited suitability for decentralized and real-time monitoring motivate the development of complementary sensing technologies. In this context, optical (bio)sensors, particularly fluorescence-based platforms, have attracted increasing attention due to their high sensitivity, rapid response, and potential for on-site monitoring. This review discusses recent advances in fluorescent optical (bio)sensors for WBE, with a particular focus on carbon dots (CDs), including waste- and biomass-derived CDs produced via green synthesis as well as CDs obtained from commercial chemicals. The applicability of CD-based sensors to wastewater-relevant analytes is evaluated, highlighting current achievements, as well as existing limitations and challenges related to real-sample validation and the translation of these platforms into robust, field-deployable systems for their implementation in sustainable wastewater monitoring and public health surveillance.
Source: Sensors
DOI: 10.3390/s26082362
Authors: Ricarda Torre, Luís Pinto da Silva
Institution: Universidade do Porto
Language: English
Subfield: Materials Chemistry
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $3,137
OpenAlex ID: W7154156942