Year: 2026
Type: article
Abstract: 2-methylcamalexin, a novel derivative of the phytoalexin Camalexin, was synthesized for the first time, using a convenient two-step approach. The approach realizes coupling of two aromatic heterocyclic moieties (2-methylindole and thiazole) by sequential α-amidoalkylation/oxidative re-aromatization. The target product was obtained in a cost-effective manner, with 88% yield over two steps. The structure of the synthesized product was unequivocally determined on the basis of NMR, HRMS and FTIR spectral measurments.
Source: Molbank
DOI: 10.3390/m2163
Institution: Plovdiv University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $603
OpenAlex ID: W7154186044