Work

1,2,6‐Thiadiazin‐4‐ones: Robust Photocatalysts for the Green Aerobic Oxidation of Sulfides to Sulfoxides

Year: 2026

Type: article

Abstract: The chemoselective oxidation of sulfides to sulfoxides is accomplished using a new family of photocatalysts, namely 1,2,6‐thiadiazin‐4‐ones. Utilizing a low catalyst loading (0.01 mol%), a 440 nm lamp as the irradiation source, and molecular oxygen as the oxidant, this rapid method is applicable to a broad range of alkyl‐aryl, dialkyl, and diaryl sulfides. Additionally, the method demonstrates practical relevance for the industrially significant synthesis of pharmaceutical compounds, including modafinil and sulforaphane.

Source: European Journal of Organic Chemistry

DOI: 10.1002/ejoc.70448

Authors: Charikleia I. Karaousta, Stamatis K. Serviou, Chrysanthi K. Spyropoulou, Nikolaos Stavridis, Andreas S. Kalogirou, Panayiotis A. Koutentis, Christoforos G. Kokotos

Institutions: National and Kapodistrian University of Athens, European University Cyprus, University of Cyprus

Language: English

Topic: Chemical Synthesis and Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,330

OpenAlex ID: W7154223016

FWCI: 1.871

Cites: 73

Cited by: 1

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