Monthly versus Bimonthly Bioelectrical Impedance Analysis for Dry Weight Assessment and Intradialytic Hypotension: A Randomized Crossover Trial
Year: 2026
Type: article
Study designs: Randomized Controlled Trial, Clinical Trial
Abstract: Introduction: Intradialytic hypotension (IDH) is a major complication during hemodialysis (HD), leading to arrhythmias and increased mortality. Inaccurate dry weight (DW) adjustment contributes to IDH. Bioelectrical impedance analysis (BIA) is commonly used to assess body composition, including fluid compartments, aiding in DW measurement. However, the measurement interval of BIA measurement to reduce IDH remains unclear. Methods: This single-center, randomized crossover trial enrolled 94 end-stage kidney disease patients on HD, and 82 of them completed the protocol. Participants were divided into two groups: group 1 underwent BIA monthly for 4 months, then bimonthly twice; group 2 started with BIA bimonthly twice, then monthly for 4 months. A 1-month washout period was implemented before switching measurement frequencies. The primary outcome was to determine if bimonthly BIA reduced IDH as effectively as monthly BIA. Secondary outcomes assessed factors influencing IDH. Results: = 0.59) analyses. Factors increasing IDH risk included older age, comorbidities including diabetes, dyslipidemia, and ischemic heart disease, elevated pre-dialysis blood pressure, and high net ultrafiltration. Additionally, lower hemoglobin, sodium, and albumin levels significantly elevated IDH incidence. Conclusion: There was no significant difference in the incidence rate of IDH between monthly and bimonthly BIA measurements.
Source: Kidney Diseases
DOI: 10.1159/000551997
Institutions: Thammasat University, Thammasat University Hospital
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,320
Funder: Thammasat University
OpenAlex ID: W7154236395
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