Work

A case report of BCR-ABL(+) acute myeloid leukemia and literature review

Year: 2026

Type: article

Abstract: BCR-ABL(+) acute myeloid leukemia (AML) is considered a rare AML subtype with a short median survival time and poor prognosis. Currently, there is no unified standard treatment regimen for this disease, which complicates clinical diagnosis, treatment and medication selection. Case reports on this AML subtype remain relatively scarce to date. In this study, we present a case of BCR-ABL(+) AML that was treated with a TKI in combination with chemotherapy to induce remission, followed by allogeneic hematopoietic stem cell transplantation (Allo-HSCT). We also review the relevant literature to shed light on treatment strategies for BCR-ABL(+) AML and provide strong support for Allo-HSCT as a therapeutic option for this subtype.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2026.1772154

Authors: Jianping Li, Wei Zheng, Xueyan Dong, Jingyi Wang, Kui Liu

Institution: Affiliated Hospital of Shandong University of Traditional Chinese Medicine

Language: English

Topic: Acute Myeloid Leukemia Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801