Work

Converting 1,1‐Bisborylalkanes into 1,2‐Bisborylalkanes Enabled by Iron Ligand‐to‐Metal Charge Transfer (LMCT) Photocatalysis

Year: 2026

Type: article

Abstract: We report herein a strategy to convert 1,1-bisborylalkanes into 1,2-bisborylalkanes through iron ligand-to-metal charge transfer (LMCT) photocatalysis. Under the optimized conditions, 1,1-bisborylalkanes undergo hydrogen atom abstraction to generate an initial radical intermediate. Subsequent radical-induced 1,2-boryl group migration furnishes an open-shell species that is more stable thermodynamically. The resulting carbon-centered radical can be intercepted by electron-deficient alkenes, affording a range of synthetically useful 1,2-bisborylalkanes.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.202524873

Authors: Zheye Zhang, George Chen, Michael Li, Carla Slebodnick, Diego Troya, Ming Chen

Institution: Virginia Tech

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $5,510

Funders: National Science Foundation, National Institutes of Health