Work

Combined mode-kinetic chain exercise with and without core stability exercises on patients with knee osteoarthritis

Year: 2026

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: BACKGROUND: Among adult population, the osteoarthritis (OA) of knee is the major issue that can lead to pain, functional limitations, and reduced quality of life. Exercise therapy is a core component of management, yet the added value of core stability training in conjunction with kinetic chain exercises remains underexplored. OBJECTIVE: To determine the effects of combined mode kinetic chain exercise with and without core stability training on pain, range of motion and quality of life in patients with knee OA. METHODS: A total of 48 patients with osteoarthritis in their knees were the subjects of a randomized controlled experiment at PSRD Hospital in Lahore were randomly allocated to either Group B (kinetic chain exercise only) or Group A (kinetic chain exercise with core stability training) with 24 participants each. For 12 weeks, interventions were carried out three times a week. Quality of life (KOOS), knee range of motion (goniometry), and pain (NPRS) were evaluated at baseline, six weeks, and twelve weeks. RESULTS: Group A and B both groups showed significant improvements in NPRS, ROM, and KOOS scores over time (p < 0.05). At 12 weeks, Group A demonstrated a greater reduction in pain compared to Group B (p = 0.002). Flexion ROM improved by 19.6° ± 3.2° in Group A versus 12.4° ± 2.9° in Group B (p < 0.001). KOOS total score increased by 34.8 ± 5.6 in Group A and 25.7 ± 5.1 in Group B (p < 0.001). CONCLUSION: Incorporating core stability exercises into a kinetic chain exercise program yields superior improvements in pain reduction, knee range of motion and quality of life in knee osteoarthritis patients compared to kinetic chain exercises alone. TRIAL REGISTRATION: The study was registered at Clinical trial.gov and was submitted on 2024–04-18. Trial Registry number was NCT06377813.

Source: BMC Musculoskeletal Disorders

DOI: 10.1186/s12891-026-09531-4

Authors: Maryam Maqsood, Jannat Sohail, Syeda Aiman Batool

Institutions: Riphah International University, Government College University, Faisalabad, University of Lahore

Language: English

Topic: Osteoarthritis Treatment and Mechanisms

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,090