Year: 2026
Type: article
Abstract: structure and the resulting near-infrared (NIR) absorption performance. Nevertheless, the NIR absorption peaks of traditional PB-based nanomedicines are often located in the NIR-I region (700-900 nm) rather than NIR-II region (900-1700 nm), thus limiting their efficacy in treating deep lesions. Herein, curcumin (Cur)-functionalized PB nanomedicine is elaborately designed for NIR-II PTT against bacterial infections. In addition to serving as a dispersant and a reducing agent, the introduced Cur effectively regulates the absorption peak of PB to the NIR-II region. Moreover, as-prepared Cur-functionalized PB nanomedicine demonstrated superior photothermal antibacterial performance against S. aureus. Therefore, this study proffers a new attempt centered on the optical performance regulation of PB and lays the foundation for next-generation PTT nanomedicines.
Source: Discover Nano
Authors: Zhouhua Li, Guanhua Sun, Fei Ge, Yuanyuan Shen, Xiuying Yang, Bing Yao, Caixia Yu, Shihong Su, Junlie Yao, Yong Wang
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,090
Funder: Anhui Medical University
OpenAlex ID: W7154457028