Year: 2026
Type: article
Study design: Case Report
Abstract: This article presents a novel technique for shaping advanced platelet-rich fibrin (A-PRF) to precisely fill uniform defects while preserving its biological integrity and regenerative capacity, with relevance to Oral & Maxillofacial Surgery. We present two clinical cases illustrating the use of soft tissue punch biopsy tools to accurately shape A-PRF plugs. In each case, appropriately sized punches were used to conform A-PRF to the dimensions of the defect—screw holes following bimaxillary osteotomy, and a sinus tract resulting from post-radiotherapy wound breakdown. The technique enabled precise, easy handling of A-PRF while maintaining its natural structure and biological properties, avoiding the loss of growth factors typically associated with compression. This technique offers a straightforward, predictable method for shaping A-PRF to precisely fit uniform cylindrical defects while preserving the natural fibrin architecture. It has the potential to simplify operative handling and optimise defect adaptation, facilitating optimal healing.
Source: Discover Medicine
Authors: Sarika Shivji, Tara Gulshan, Valmiki Sharma
Language: English
Subfield: Urology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,290
OpenAlex ID: W7154457783