Work

The current landscape of therapeutic vaccination approaches for treatment of HPV-dependent malignancies

Year: 2026

Type: article

Abstract: This review provides an overview of current therapeutic human papillomavirus (HPV) vaccination approaches. We review important criteria for their development, and present vaccines currently being actively followed in clinical trials, for precursor lesions or established cancers. Subsequently, we list approaches that reached clinical trial stage but were abandoned. Lastly, we discuss promising preclinical studies. We conclude with a brief overview of novel in silico tools developed to enhance vaccine design.

Source: npj Vaccines

DOI: 10.1038/s41541-026-01426-8

Authors: Johanne Audouze-Chaud, Ann-Katrin Schlosser, Angelika B. Riemer

Institutions: German Cancer Research Center, Heidelberg University, German Center for Infection Research

Language: English

Topic: Cervical Cancer and HPV Research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,890