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Divergent Paths: A Comprehensive Review of Mechanisms and Clinical Implications in Atopic Dermatitis and Psoriasis

Year: 2026
Type: article
Abstract: Atopic dermatitis and psoriasis are two common cutaneous chronic inflammatory diseases. Although they share similar immunological mechanisms, their clinical implications in the patient are different. This review compares both diseases from different points of view such as genetics, natural history, triggers of disease, and skin barrier defects among other disease aspects. The lessons learned by translational research using targeted therapies have also contributed to clarifying differences.
Source: Allergy
DOI: 10.1111/all.70347
Authors: Tali Czarnowicki, Kazunari Sugita, Zenas Yiu, Sandra Díez‐Ribas, Irene Garcia‐Jimenez, Emma Guttman‐Yassky, Luis F. Santamaria‐Babí
Institutions: University of Miami, Saga University, Manchester Academic Health Science Centre, University of Manchester, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Universitat de Barcelona, Icahn School of Medicine at Mount Sinai
Language: English
Subfield: Dermatology
Field: Medicine
Open Access status: hybrid
Estimated APC paid: $5,300
OpenAlex ID: W7154487486
FWCI: 13.02
Cites: 160
Cited by: 2
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