Work

Discovery of New Teraryl γ-Lactam Derivatives as Potent Antibacterial Agents In Vitro and In Vivo through Dual Cell Wall–Membrane Inhibitions

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c00136

Authors: Lishu Sheng, Yue Yuan, Taopeng Chang, Yitong Hu, Fang Li, Zhifu Chen, Jingwen Liao, Dianyan Chen, Feifei Chen, Jinhua Dong, Yongxu Zhao, Jinyong Zhang, Dongliang Guan

Institutions: Shenyang Pharmaceutical University, Army Medical University, Anhui University of Traditional Chinese Medicine, Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences

Language: English

Topic: Antimicrobial Resistance in Staphylococcus

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Chinese Academy of Sciences, Taishan Scholar Foundation of Shandong Province, Key Technology Research and Development Program of Shandong

Awards: G1434230614, G2629551592, G6921424887, G7915718215

OpenAlex ID: W7154581582

FWCI:

Cites: 55

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