A robust magnetically recoverable nickel nanocatalyst for α-olefination of nitriles using primary alcohols
Year: 2026
Type: article
Abstract: A novel nickel nanocatalyst with a magnetic core was designed and synthesized through a multi-step procedure. First, an iron oxide core was synthesized (Fe 3 O 4 ), then coated with a silica layer (Fe 3 O 4 @SiO 2 ). The catalyst support was further functionalized using epichlorohydrin (EP) and ortho -phenylenediamine (OPDA) (Fe 3 O 4 @SiO 2 /EP/OPDA), and finally, nickel was loaded onto the structure to obtain the finished catalyst (Fe 3 O 4 @SiO 2 /EP/OPDA@Ni). Its successful fabrication was confirmed by various characterization techniques, including X-ray diffraction, transmission electron microscopy, energy-dispersive X-ray spectroscopy, and vibrating-sample magnetometry. The nanocatalyst was then effectively applied in the α-olefination of nitriles using primary alcohols through the reaction of a benzyl alcohol derivative with a benzyl cyanide derivative in refluxing toluene, using KO t -Bu as the base. The catalyst could be easily separated from the reaction mixture by applying an external magnetic field. It was also reusable, retaining its activity with only a minor loss over at least five consecutive cycles.
Source: Transition Metal Chemistry
Authors: Effat Vatankhah, Hossein Eshghi, Ali Shiri
Institution: Ferdowsi University of Mashhad
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
Funder: Ferdowsi University of Mashhad
Award: G5414628822
OpenAlex ID: W7154604493