Year: 2026
Type: article
Abstract: In this issue of Blood, Carturan et al 1 have developed a novel CD2-targeting chimeric antigen receptor (CAR) construct including knock-out of CD2, to prevent fratricide of CAR T cells, and a novel programmed cell death protein 1 (PD-1):CD2 switch receptor to restore the CD2-CD58 signaling axis critical for T-cell activity.
Source: Blood
Author: Borhane Guezguez
Language: English
Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W7154617406