Work

Metabolic Outcomes and Recurrent Weight Gain 10 Years After Roux-en-Y Gastric Bypass, a Longitudinal Cohort Study

Year: 2026

Type: article

Abstract: INTRODUCTION: Long-term weight loss and improvement in associated medical problems are seen after metabolic bariatric surgery (MBS) as Roux-en-Y gastric bypass (RYGB). Few studies have focused on recurrent weight gain (RWG) after RYGB. METHODS: Patients operated with RYGB from 2004 to 2008 were invited to 10-year follow-up consultations. The primary outcome was weight development in terms of total weight loss and RWG. Significant RWG was defined as gaining > 30% of initial weight loss two years postoperatively. Secondary outcomes included associated medical problems. RESULTS: Among a total of 582 patients operated, 311/544 (56%) patients attended 10-year follow-up. Mean age at 10 years was 52.8 (9.2) years, with 76.5% females. Body mass index (BMI), weight and total weight loss at 10-year follow-up were 35.6 (6.8) kg/m2, 103.7 (24.1) kg and 23.4 (12.3) %, respectively. RWG at 10-year follow-up was 26.0 (48.8) %, with 45.6% of the patients experiencing RWG > 30%. For patients with and without RWG > 30%, the relapse and remission rates of diabetes type 2 and hypertension were comparable. Relapse rates of dyslipidemia were higher in patients with RWG > 30%. CONCLUSION: We found a high prevalence of significant RWG 10 years after RYGB. Except for dyslipidemia, the metabolic benefits of RYGB persisted despite RWG.

Source: Obesity Surgery

DOI: 10.1007/s11695-026-08662-w

Authors: Monica Chahal-Kummen, Stephen Hewitt, Torgeir Thorson Søvik, Jon Kristinsson, Tom Mala

Institutions: Oslo University Hospital, University of Oslo

Language: English

Topic: Bariatric Surgery and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,590