Work

Discovery of Potent Benzoselenazinone-Based DprE1 Inhibitors: A Novel Selenium-Containing Scaffold with Superior Anti-TB Activity and Pharmacokinetic Properties

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c03770

Authors: Yang Liu, Xiuli Xu, Chengxia Mao, Bin Wang, Mario Cocorullo, Andrea Tresoldi, Matteo Mori, Baolian Wang, Yu Lu, Haihong Huang, Laurent R. Chiarelli, Peng Li

Institutions: Chinese Academy of Medical Sciences & Peking Union Medical College, Capital Medical University, Beijing Chest Hospital, University of Pavia, University of Milan

Language: English

Topic: Organoselenium and organotellurium chemistry

Subfield: Toxicology

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Chinese Academy of Medical Sciences, Beijing Municipal Natural Science Foundation

Awards: G4339664968, G6726299619

OpenAlex ID: W7154682969

FWCI:

Cites: 36

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