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Abstract CT120: A phase 1 study of BGB-24714, a second mitochondrial-derived activator of caspases (SMAC) mimetic, as monotherapy or in combination with chemotherapy or concurrent chemoradiotherapy in solid tumors

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Year: 2026
Type: conference-abstract
Source: Cancer Research
DOI: 10.1158/1538-7445.am2026-ct120
Authors: Andreas Varkaris, Erika Hamilton, Jermaine Coward, Rafael Santana-Davila, Jinming Yu, Byoung Chul Cho, Jung Yun Lee, Yongsheng Li, Sanjeev Deva, Youngjoo Lee, Huai Liu, Yuping Sun, Zhe Yang, Wen Xu, Sook Ryun Park, Se-Hoon Lee, Andrew Z. Wang, Hui Shao, Jinhui Zhang, Zhaoyin Zhu, Runzhe Chen, Hua-Xin Gao, Judy S. Wang
Institutions: Massachusetts General Hospital, Sarah Cannon, Icon (Australia), Fred Hutch Cancer Center, Shandong Tumor Hospital, Severance Hospital, Yonsei University Health System, Chongqing Cancer Hospital, National Cancer Center, Hunan Cancer Hospital, Shandong Provincial Hospital, Princess Alexandra Hospital, Asan Medical Center, Samsung Medical Center, The University of Texas Southwestern Medical Center
Language: English

Topic: Cell death mechanisms and regulation
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W7154688011
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