Pan-immune inflammation value and system inflammation response index associated with prolonged hospital stay of thyroid nodule patients undergoing ultrasound-guided microwave ablation, both aged ≤55 years and > 55 years
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background The preoperative immune inflammatory status may affect the prognosis of thyroid nodule patients performed ultrasound-guided microwave ablation therapy. The aim of this study is to analyze the relationship between the pan-immune inflammation value (PIV), systemic immune inflammation index (SII), and system inflammation response index (SIRI) and the prolonged hospital stay of patients after microwave ablation. Methods 1288 patients who underwent ultrasound-guided microwave ablation for thyroid nodules from October 2017 to March 2024 were retrospectively analyzed. The patients were divided into prolonged hospital stay group (hospital stay >1 day) and non-prolonged hospital stay group (1 day). Receiver operating characteristic (ROC) curve analysis was performed to assess the diagnostic efficacy of PIV, SII and SIRI in predicting prolonged hospital stay. Logistic regression analysis was applied to examine the relationship of PIV, SII, SIRI with prolonged hospital stay. Results The levels of PIV, SII, and SIRI in prolonged hospital stay group were higher than those in non-prolonged hospital stay group. The cut-off value of PIV, SII, and SIRI was 190.56, 541.31, and 0.845 based on ROC curve analysis, respectively. In subjects with age ≤55 years, logistic regression analysis showed that high PIV (odds ratio (OR): 2.119, 95% confidence interval (CI): 1.389-3.232, p < 0.001), SII (OR: 1.678, 95% CI: 1.173-2.400, p = 0.005) and SIRI level (OR: 1.948, 95% CI: 1.316-2.882, p = 0.001) were associated with prolonged hospital stay. In age >55 years old, diabetes mellitus (OR: 1.720, 95% CI: 1.002-2.950, p = 0.049), high PIV (OR: 1.961, 95% CI: 1.086-3.541, p = 0.026) and SIRI (OR: 1.840, 95% CI: 1.015-3.335, p = 0.044) were significantly associated with prolonged hospital stay. Conclusions PIV and SIRI are associated with the prolonged hospital stay of thyroid nodule patients undergoing ultrasound-guided microwave ablation, both aged ≤55 years and > 55 years.
Source: Frontiers in Endocrinology
Authors: Mingwei Song, Sirong Lan, Hui Rao, Yeqian Lai
Institution: Meizhou City People's Hospital
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W7154700516