Work

Imported Pediatric Lyme Disease in Singapore—A Case Series

Year: 2026

Type: article

Abstract: Lyme disease is the most common reported vector-borne disease in North America and is also highly prevalent across Europe. Although tick-borne diseases are uncommon in Singapore, there remains a risk of imported tick-borne diseases among travelers from endemic regions. We present a case series of three pediatric patients with imported Lyme disease managed at a tertiary children's hospital in Singapore, illustrating the varied clinical presentations of Lyme disease in children. One child developed meningitis following prior antibiotic therapy for Lyme disease, although causality cannot be definitively established. This series aims to highlight key diagnostic considerations and management principles relevant to clinicians practicing in non-endemic regions.

Source: Pathogens

DOI: 10.3390/pathogens15040437

Authors: Ade Xin Ning Tan, Ilyas Hussin, Chia Yin Chong, Matthias Maiwald, Terri Xiao-Bei Chiong, Natalie Woon Hui Tan

Institutions: KK Women's and Children's Hospital, National University of Singapore, Nanyang Technological University, Duke-NUS Medical School

Language: English

Topic: Vector-borne infectious diseases

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,654