Work

Case Report: A Case of Intravenous Leiomyomatosis Involving the Inferior Vena Cava and Right Atrium

Year: 2026

Type: article

Abstract: Intravenous leiomyomatosis (IVL) is rare and is characterized by the extension of an aggressive, histologically benign tumor into venous channels and cardiac chambers. We report a case of advanced IVL to highlight its insidious presentation and the requisite multidisciplinary surgical approach. A patient presenting with nonspecific symptoms was incidentally diagnosed with stage III IVL with intracardiac extension. A multidisciplinary team performed a single-stage procedure that involved a total hysterectomy with bilateral adnexectomy and left ovarian vein resection, followed by right atrial tumor resection under extracorporeal circulation (without cardiac arrest), IVC tumor removal, and resection of a left renal vein tumor embolus. The surgery was successful, with an uneventful recovery. This case highlights that IVL can be asymptomatic until it reaches an advanced stage. A meticulous, single-stage multidisciplinary surgical strategy is feasible and effective for complete tumor resection, even in the presence of intracardiac involvement, ensuring optimal patient outcomes.

Source: SN Comprehensive Clinical Medicine

DOI: 10.1007/s42399-026-02370-3

Authors: Xiaoshi Wang, Qingsong Zhang, Jinwei Zhang

Institutions: Nanjing Medical University, Wuxi People's Hospital

Language: English

Topic: Uterine Myomas and Treatments

Subfield: Obstetrics and Gynecology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,090