Work

Discovery of Highly Potent Phthalazinone Derivatives as PARP14 Inhibitors: From Structure-Based Virtual Screening to In Vivo Pharmacodynamic Activity

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c00004

Authors: Shiqi Wu, Kaiyuan Cong, Jing Liu, Le Qu, Xiaorong Zeng, Xiangying Kong, Ziyue Li, Shaoxue Lou, Ping Wei, Li Shao, Hongfeng Gu, Yan Zhao, Qinlong Xu, Zhaoxing Chu, Guangwei He, Qihua Zhu, Yungen Xu, Yi Zou

Institutions: China Pharmaceutical University, State Key Laboratory of Natural Medicine

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Computational Theory and Mathematics

Field: Computer Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7155017189

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Cites: 24

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