Year: 2026
Type: article
Abstract: Mutations in genes encoding RNA splicing factors are common in patients with myeloid malignancies and chronic lymphocytic leukemia. In this commentary, we discuss key unanswered questions on the causal role of these mutations in blood cancers and precursor conditions as well as efforts to develop therapies targeting these high-frequency neomorphic mutations.
Source: Blood Cancer Discovery
Authors: Maxim I. Maron, Omar Abdel-Wahab
Institution: Memorial Sloan Kettering Cancer Center
Language: English
Topic: RNA Research and Splicing
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W7155046419