Work

Design, Synthesis and Biological Evaluation of 6H-Benzimidazo[1′,2′:1,2]pyrido[3,4- b ]indole Derivatives as TDP1 Inhibitors: Potent Synergistic Agents with Topotecan against Cervical Cancer

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c00016

Authors: Huang Zeng, Bo Qiu, Jiunlong Yang, Yuman Xie, Hui Huang, Shengyuan Zhang, Hua Nie, Nan Wang, Zeyong Huang, Lingfeng Wu, Jiayao Liu, Xuerou Zheng, Yuanbei Zhuang, Hao Yang

Institutions: Jiaying University, Third Affiliated Hospital of Sun Yat-sen University, Ningxia Medical University

Language: English

Topic: Cancer therapeutics and mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Department of Education of Guangdong Province, Traditional Chinese Medicine Bureau of Guangdong Province, Science and Technology Planning Project of Guangdong Province, Basic and Applied Basic Research Foundation of Guangdong Province

Awards: G2165391683, G2471137833, G2518371026, G3624672095, G8263626896

OpenAlex ID: W7155050263

FWCI: 1.842

Cites: 40

Cited by: 1

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