Serological insights of Crimean-Congo haemorrhagic fever virus in podolic cattle bred in Italy
Year: 2026
Type: article
Abstract: , formerly Crimean-Congo haemorrhagic fever virus (CCHFV) in the serum of podolic cattle from southern Italy. A subset of 20 sera (18 positive and 2 negative) from the initial 670 bovine samples screened by commercial ELISA kit were further evaluated by indirect ELISA and virus neutralization tests. Across the three serological assays, antibodies against CCHFV were detected in a proportion of samples, though the results were not fully concordant and varied according to the assay applied. These findings highlight the need for multiple tests to more accurately assess CCHFV circulation in free-range cattle, particularly in non-endemic areas, and emphasize the importance of careful interpretation when relying on serology alone.
Authors: Donato Antonio Raele, Kerstin Fischer, Julia Holzerland, Caroline Bost, Domenico Scaltrito, Antonio Parisi, Donatella Belluscio, Anna Mattea D’Antuono, Lara Caprarella, Antonella Narducci, Goffredo Sarti, Domenico Pugliese, Michela Sordillo, Guido Di Donato, Maria Assunta Cafiero, Nicola Cavaliere
Language: English
Topic: Viral Infections and Vectors
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,801
OpenAlex ID: W7155076805