Work

Plaque-Type Psoriasis Induced by Non-Steroidal Aromatase Inhibitor (Letrozole): A Case Series

Year: 2026

Type: article

Abstract: Psoriasis is a multifactorial disease triggered by various factors, including medications. Letrozole is an effective adjuvant hormonal therapy used in the treatment of breast cancer and has been linked to different skin eruptions. However, psoriasis is not a well-established side effect. We describe two patients with similar manifestations of plaque psoriasis. Both cases were confirmed through histological examination. This case report highlights the importance of recognizing letrozole as a possible cause of plaque psoriasis.

Source: Cureus

DOI: 10.7759/cureus.107454

Authors: Gaeda K Alkaltham, Amnah N Almulhim, Lenah Y Shaikh, Musaed Alsebayel

Institution: King Fahad Specialist Hospital

Language: English

Topic: Psoriasis: Treatment and Pathogenesis

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7155095309