Work

PRMT5 Inhibition by SCR-6920 Downregulates HIF-1α and Exhibits Synergistic Antitumor Activity with Bevacizumab in Ovarian Cancer

Year: 2026

Type: article

Source: Molecular Cancer Therapeutics

DOI: 10.1158/1535-7163.mct-25-1105

Authors: Guimei Yang, Huixia Dou, Liting Xue, Weijie Chen, Yao Guo, Grace Xue, Ying Sun, Hanxiao Shi, Jian Li, Jianing Song, Zhen Li, Congjun Zhang, Renhong Tang, Feng Zhou

Institutions: Anhui Medical University, First Affiliated Hospital of Anhui Medical University, Simcere Pharmaceutical (China)

Language: English

Topic: Cancer-related gene regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7155102022

FWCI:

Cites: 48

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