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Vitex agnus-castus extract improved the endocrine profile and important gene expression in rat ovaries with polycystic ovary syndrome.

Year: 2026

Type: article

Abstract: Objective: gene expression in the ovaries of a rat model of PCOS. Materials and Methods: gene expression. Results: was significantly (p=0.0001) higher in the ovaries of the PCOS group compared to other groups, and consumption of the extract improved the evaluated parameters significantly. Conclusion: The endocrine profile and gene expression were improved in the rat ovary following administration of VE, and therefore, the therapeutic effect of VE may be expected in PCOS.

Source: PubMed

DOI: 10.22038/ajp.2025.26622

Authors: Mahtab Abbaszadeh, Gholamali Jelodar, Aazam Salmani, Saeid Hosseinzadeh

Institution: Shiraz University

Language: English

Topic: Ovarian function and disorders

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7155107272

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