Work

Design, Synthesis and Biological Evaluation of Potent Piperazine-Based BioA Inhibitors Targeting Biotin Biosynthesis in Mycobacterium tuberculosis

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.5c03325

Authors: Qiang Liu, Curtis A. Engelhart, Joshua B. Wallach, Peng Ge, Tsung-Yun Wong, Moyosore O. Orimoloye, Suyapa Rodriguez, Yahani P. Jayasinghe, Donald R. Ronning, Véronique Dartois, Jansy P. Sarathy, Dirk Schnappinger, Matthew D. Zimmerman, Courtney C. Aldrich

Institutions: University of Minnesota, Weill Cornell Medicine, Hackensack Meridian Health, University of Nebraska Medical Center

Language: English

Topic: Synthesis and Characterization of Heterocyclic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Cancer Institute

Awards: G9000241543, G956063283

OpenAlex ID: W7155165351

FWCI: 1.813

Cites: 54

Cited by: 1

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