Work

Repetition Time and Echo Time as Determinants of Quantitative Accuracy in Brain Magnetic Resonance Spectroscopy (MRS): A Comprehensive Review

Year: 2026

Type: article

Abstract: Magnetic resonance spectroscopy (MRS) is a non-invasive technique that can be used to characterize and measure in vivo biochemical metabolites in the human brain. MRS extends the concept of conventional magnetic resonance imaging, which primarily depicts anatomical structures, to provide metabolic data vital for comprehending the physiological functioning of a normal brain as well as pathological processes such as tumors, neurodegenerative disorders, epilepsy, metabolic encephalopathies, and psychiatric illnesses. To support clinical diagnosis and metabolite research, accurate quantification of brain metabolites, such as N-acetylaspartate, choline-containing substances, creatine, myo-inositol, glutamate, glutamine, and lactate, is vital.

Source: Cureus

DOI: 10.7759/cureus.107517

Authors: Sumit Tyagi, Ashok Sharma, Ashish Kumar Shukla, Subhash Chand Sylonia, Lalit Gupta

Institutions: Santosh University, Saraswathi Institute of Medical Sciences

Language: English

Topic: Advanced MRI Techniques and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7155184111