Work

Biofilm- and Spore-Disruptive Star-Shaped Poly( l -lysine)/Hyaluronic Acid Microgels for Targeted Oral Therapy of Clostridioides difficile Infection

Year: 2026

Type: article

Abstract: microgels as a microbiota-sparing therapeutic that targets multiple stages of CDI pathogenesis─including spores and biofilms─and demonstrate their potential for clinical translation.

Source: Biomacromolecules

DOI: 10.1021/acs.biomac.5c02037

Authors: I-Fan Lin, Chia-Yang Chou, Yu-Fang Chen, Ting-Yen Wang, Jing-Ting Lin, Ching-Chi Lee, Jenn-Wei Chen, Jeng-Shiung Jan, Yuan-Pin Hung

Institutions: E-Da Hospital, National Cheng Kung University, I-Shou University, National Cheng Kung University Hospital, Tainan Hospital

Language: English

Topic: Clostridium difficile and Clostridium perfringens research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: E-Da Hospital, National Cheng Kung University Hospital, National Cheng Kung University, National Science and Technology Council

Awards: G1617538512, G3684060179, G4943858608, G5245371191, G5347122054, G5965722504, G8642981815

OpenAlex ID: W7155192747

FWCI: 4.959

Cites: 61

Cited by: 1

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