Work

IL-32 as a potential biomarker and therapeutic target in cardiovascular disease

Year: 2026

Type: article

Abstract: Cardiovascular diseases remain a leading cause of death worldwide, driven by complex pathological mechanisms involving various cytokines and inflammatory responses. IL-32, a recently discovered cytokine, has emerged as a key player in the pathogenesis of cardiovascular diseases, including atherosclerosis, myocardial infarction, and heart failure. This review summarizes the biological characteristics of IL-32 and its role in cardiovascular diseases, explores its involvement in inflammatory responses and other pathological processes, and evaluates its potential as both a biomarker and a therapeutic target. Collectively, this review aims to provide new insights for the prevention and treatment of cardiovascular diseases.

Source: Frontiers in Immunology

DOI: 10.3389/fimmu.2026.1755759

Authors: Lingyue Qiu, Jing Ye, Ling Liu, Qingwei Ji

Institutions: The People's Hospital of Guangxi Zhuang Autonomous Region, Renmin Hospital of Wuhan University

Language: English

Topic: Atherosclerosis and Cardiovascular Diseases

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801