Work

Abdominal disseminated lesions following surgery for a testicular mucinous cystic neoplasm initially diagnosed as mucinous cystadenoma: a case report and literature review

Year: 2026

Type: article

Abstract: This report describes a rare testicular mucinous cystic neoplasm in a 78-year-old man who underwent scrotal exploration and right radical orchiectomy. Histopathology of the resected specimen was interpreted as an ovarian-type mucinous cystadenoma with focal epithelial proliferation. Six months after surgery, follow-up imaging demonstrated multiple abdominal and peritoneal lesions suspicious for disseminated disease. Because the abdominal lesions were diagnosed radiologically and were not histologically sampled, metastatic disease could not be pathologically confirmed. In addition, immunohistochemical analysis of the orchiectomy specimen was not performed, and a gastrointestinal primary tumor was not definitively excluded by endoscopic evaluation. The case highlights the diagnostic challenges of distinguishing benign, borderline, malignant, and metastatic mucinous tumors involving the testis, and it emphasizes the importance of postoperative surveillance, comprehensive clinicopathologic correlation, immunohistochemistry, and exclusion of an extratesticular primary site.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2026.1731890

Authors: Junjie Yang, Weida Li, Jian Wang, Jianchang Li

Institution: Guangdong Medical College

Language: English

Topic: Testicular diseases and treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801