Work

Natural Aging of Biomaterials in Ambient and Physiological Environments

Year: 2026

Type: article

Abstract: Biomaterials, generally defined as materials that interact with biological systems, are ubiquitous in the field of biomedical engineering. Biomaterials can undergo natural aging, in which changes in material properties occur in near‐ambient or near‐physiological environments without external acceleration. This can be either beneficial or harmful to the material or the tissue that interacts with the material. Such natural aging depends on material composition, temperature, pH, storage media composition, sterilization, and numerous other factors. This review focuses on studies investigating the natural aging of polymers, metals, ceramics, and nanomaterials, and their impact on material characteristics and functions as biomaterials.

Source: Advanced NanoBiomed Research

DOI: 10.1002/anbr.202500198

Authors: Shuyu Zhang, Anne E. Staples

Institutions: Virginia Tech - Wake Forest University School of Biomedical Engineering & Sciences, Virginia Tech

Language: English

Topic: Bone Tissue Engineering Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $3,940

Funders: Virginia Polytechnic Institute and State University, National Institute of Biomedical Imaging and Bioengineering